Busy work and frequent socializing make people overwhelmed, while smoking and drinking accompany them. Some people may experience physical discomfort when drinking a small amount of alcohol, while others can drink a thousand cups without pouring. Some people smoke or smoke secondhand smoke, which can lead to respiratory diseases, while others are "longevity smokers.". Similarly, smoking and drinking can cause some people to get sick or even die, while others can live a long and healthy life. Modern medicine shows that due to genetic differences among individuals, the damage caused by smoking and alcohol varies from person to person. Genetic testing allows you to understand the extent of the impact of smoking and drinking on your own health, reducing the risk of illness.
The First Health Killer - Cigarettes
Knowing the harm of cigarettes, let's now take a look at CYP2E1. CYP2E1 is a gene in the human body that encodes enzymes that can activate pre carcinogens in tobacco - nitrosamines, causing them to have carcinogenic effects. Individuals with missing CYP2E1 genotypes will increase their activity, thereby increasing the risk of lung cancer.
Although smoking poses significant risks, the risk of drinking alcohol should not be underestimated. Drinking alcohol not only damages male reproductive ability, but also harms the liver.
And ALDH2 is closely related to it. ALDH2 is an aldehyde dehydrogenase that participates in alcohol metabolism, catalyzing acetaldehyde to acetic acid, ultimately forming water and carbon dioxide. When the gene undergoes a mutation, the state of alcohol metabolism will be greatly different, and the liver is the main site of alcohol metabolism. 90% of the alcohol consumed by the body is metabolized in the liver, so ALDH2 mutations are closely related to the formation of liver disease.
Although tobacco and alcohol pose significant health risks, individual differences in immunity and enzyme activity directly lead to varying degrees of damage. Therefore, it is necessary for wind farms to have a clear understanding of their sensitivity to tobacco and alcohol, and to combine testing reports for reasonable health management. We welcome everyone to contact our company for more details.
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